328 W. Claiborne St.
P.O. Box 964
Monroeville, Alabama 36460
(251) 575-4203
     
Alzheimers Disease and other Cognitive Disorders
Resources
Basic Information
Introduction & Causes of Cognitive DisordersDementiaAlzheimer's DiseaseOther Cognitive DisordersDementia Coping Skills & Behavior ManagementTraumatic Brain Injury (TBI)Conclusion and Resources
More InformationLatest News
Alzheimer's Cases to Double by 2060: ReportGene Discovery May Help Fight Alzheimer'sCould New 'Brain Training' Program Help Prevent Dementia?Millions Could Miss Out on a Potential Alzheimer's BreakthroughSleep Apnea May Boost Alzheimer's RiskNew Finding Hints at Clue to DementiaResilient Brain Connections May Help Against Alzheimer'sAmerica's Dementia Caregivers Cite Stresses, RewardsHealth Tip: Identifying Vascular DementiaOne Type of Dementia Is Especially CostlyA More Accurate Predictor for Alzheimer's?Failing Sense of Smell Tied to Dementia RiskIs Dementia Declining Among Older Americans?Intracranial Pressure Monitoring No Benefit in Pediatric TBIGender-Specific High-Risk 'Window' Seen in Alzheimer'sWomen at Risk for Alzheimer's Face Critical 10-Year Window, Study SaysDo Fewer Nightly Dreams Mean Higher Dementia Risk in Seniors?Dementia Care: A Huge Financial Burden for U.S. FamiliesPopular Heartburn Drugs Don't Raise Risk of Alzheimer's: StudyFamilies Shoulder Majority of Costs Related to Dementia CareMidlife Vascular Risk Factors Tied to Increased Risk of DementiaMidlife Behaviors May Affect Your Dementia RiskTraveling With Dementia: Tips for Family CaregiversHigher Risk of Dementia Seen in Those Hailing From 'Stroke Belt'Health Tip: Alzheimer's Affects SleepNoninvasive Brain Test May Pinpoint Type of DementiaTargeting 9 Risk Factors Could Prevent 1 in 3 Dementia Cases: StudyAAIC: Rx + Training Shows Benefit in Advanced Alzheimer'sAAIC: Alzheimer Biomarkers Up With Sleep Disordered BreathingDozens of Potential Alzheimer's Meds in the PipelineSpecial Training Plus Medication Might Help People With Advanced Alzheimer'sSleep Problems: An Early Warning Sign of Alzheimer's?PPIs Not Found to Raise Risk of Alzheimer's DiseasePopular Heartburn Meds Don't Raise Alzheimer's Risk: StudyLifestyle Changes Might Prevent or Slow DementiaSevere Headaches Plague Vets With Traumatic Brain InjuriesSticky Brain 'Plaques' Implicated in Alzheimer's Again'Making the Best of It': Families Face the Heavy Burden of Alzheimer'sCognitive Decline Linked to Visual Field VariabilityAlzheimer's Deaths Jump 55 Percent: CDCLife Expectancy Slighter Shorter With Parkinson's, DementiaLow Body Mass Index Not Risk Factor for Alzheimer's DiseaseWives, Daughters Shoulder Most of Alzheimer's Care BurdenGene Mutation May Speed Alzheimer's DeclineSilent Seizures May Contribute to Alzheimer's Pathology'Silent' Seizures Tied to Alzheimer's SymptomsPsychiatric Scars of Wartime Brain Injury May Linger for YearsMany Patients With Alzheimer's Disease Discontinue AChEIsAntipsychotic Medication Use Can Be Reduced in Dementia PatientsPast Psychiatric Disorders Do Not Raise Risk of Alzheimer's Disease
Links
Related Topics

Aging & Geriatrics
Memory Problems
Elder Care

Vitamin E, Selenium Supplements Won't Curb Men's Dementia Risk

HealthDay News
by By Alan MozesHealthDay Reporter
Updated: Mar 20th 2017

new article illustration

MONDAY, March 20, 2017 (HealthDay News) -- A daily dose of vitamin E or selenium supplements won't keep dementia at bay in older men, new research reveals.

"After an average of five years of supplementation, and up to 11 years of follow-up, we did not observe fewer new cases of dementia among men who took any of the supplements compared to neither supplement," said study co-author Frederick Schmitt. He's a professor with the Sanders-Brown Center on Aging and the department of neurology at the University of Kentucky in Lexington.

"Based on these results, we do not recommend vitamin E or selenium supplements to prevent dementia at these doses," he added.

Approximately 5 million American seniors are now living with Alzheimer's, the study authors noted.

Selenium is an essential antioxidant, according to the U.S. National Institutes of Health (NIH). It's involved in promoting hormone metabolism, as well as protecting against infection and oxidative damage. Vitamin E is thought to boost immunity and protect against cell damage. Both are naturally found in many foods, the NIH said.

Unlike prescription medications, supplements aren't regulated by the U.S. Food and Drug Administration for safety or effectiveness.

Researchers initially became interested in vitamin E and selenium because of their antioxidant properties. Antioxidants can help prevent damage to some cells. The study team hoped that this would be true for the brain cells involved in dementia.

Schmitt said his team was "not aware of specific supplement makers that market vitamin E or selenium for brain health."

Between 2002 and 2008, the study enrolled slightly more than 7,500 males across the United States (including Puerto Rico) and Canada. All were aged 60 or older. None had a history of neurological problems, dementia, serious head injury or substance abuse.

Participants were divided into four groups: a vitamin E group; a selenium group; a combination group; and a placebo group (the "control" group).

The supplement doses were 400 international units (IUs) of vitamin E and 200 micrograms of selenium per day.

The men took the supplements or the placebo for an average of about five years, the study authors said.

Study participants underwent annual in-person memory screenings and, sometimes, secondary mental health screenings. Starting in 2008, and continuing through 2014, a smaller sub-group of roughly 4,300 participants continued memory screenings by phone.

In the end, 325 men developed dementia at some point during the study. Of these, 71 had been in the vitamin E group, 78 in the selenium group, 91 in the combination group, and 85 in the control group that took no supplements.

Schmitt said since the study didn't include women, he couldn't speculate whether the findings would apply across gender.

But, "for consumers specifically concerned about brain health and cognition, they should be aware that no scientifically rigorous studies have identified any supplement as an effective treatment or prevention for dementia," Schmitt said.

For people who want to do something, he said, "regular physical activity, such as walking, and a heart-healthy diet have much more evidence supporting their effectiveness for reducing dementia risk."

Dr. Steven DeKosky, co-author of an accompanying editorial and deputy director of the McKnight Brain Institute at the University of Florida in Gainesville, had words of advice when it comes to taking supplements for any reason: "buyer beware."

"My rule for people taking supplements is that they should check with their physicians," he said. DeKosky added that people should "not stop their prescribed medications because they were going to take something else."

Supplements can sometimes interact with prescription drugs, and "there is no proof that they work," he noted.

DeKosky also downplayed the anti-dementia potential of supplements.

"It is not a simple disease," he said, "and a simple 'silver bullet' is not to be expected."

The study was published online March 20 in JAMA Neurology.

More information

There's more on dementia at the U.S. National Institute of Neurological Disorders and Stroke.




328 W. Claiborne St.
P.O. Box 964
Monroeville,
Alabama 36460
Tel: (251)575-4203
Fax:(251)575-9459


powered by centersite dot net